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Nature Comms
A tunable dual-input system for on-demand dynamic gene expression regulation
Dynamic gene expression patterns orchestrate cellular functions. To understand the link between dynamic behaviour and cellular phenotype, and to direct cell fate in a user-defined way, tools enabling precise tuning of gene activation levels and temporal dynamics were developed.
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Nature Biotech
How will today’s patent law affect tomorrow’s innovation in the areas of biomarkers; nature-based products; diagnostics; and algorithms, big data and AI?
Behind the paper "How does the emerging patent case law in the US and Europe affect precision medicine?"
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Nature Comms
Gene therapy meets cell therapy in the fight for sight
In the eye, a tiny pit in the central retina provides us the clearest vision of all. This region contains the highest number of cone photoreceptors – responsible for our daylight, high acuity vision. Unfortunately, several diseases lead to the degeneration of these photoreceptor cells.
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Nature Comms
High levels of AAV vector integration into CRISPR-induced DNA breaks
Using next-generation sequencing, we show that adeno-associated virus (AAV) DNA can cut-and-paste into CRISPR-induced breaks in the host genome.
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Behind the paper
How a recently published research paper came to be, written by the authors.
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Translational challenges of electrical spinal cord stimulation
Spinal cord injury often results in irreversible paralysis due to blocked communication between the
brain and the spinal cord. While electrical stimulation of the spinal cord has been successfully
applied to restore motor function in animal models, electrical stimulation in humans has been less
effective for reasons not yet completely understood.
Journal surgery
News and updates about Nature Research journals publishing in biomedical engineering or biological engineering.
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The covers from the monthly issues of Nature Biomedical Engineering.
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