We all produce and discharge excretions into the sewer. Correspondingly, sewerage can tell a lot about its contributory population. In the case of the ongoing COVID-19 pandemic, wastewater-based epidemiology can serve as a tool for population wide pathogen surveillance without compliance issues.

Obtaining European patent protection for medical uses of known products is not a key factor limiting repurposing activity.

Recombinant AAV vectors are becoming more popular for therapeutic genome editing. We describe a clinically relevant approach to enhance insertion a therapeutic sequence into almost any site in the host genome.