Nature Communications
An open access, multidisciplinary journal dedicated to publishing high-quality research in all areas of the biological, health, physical, chemical and Earth sciences.
Two-input protein logic gate for biological computation
Here we design a two-input single protein logic gate for biological computation by allosterically wiring two inputs to a functional site of a protein.
Challenge-oriented design of nanoagent enabling dual-mitochondrial-damage synergistic antitumor therapy
We developed a new type of MOFs-based core-shell nanoagents that enables near infrared (NIR) light-triggered two distinct antitumor mechanisms, namely oxidative stress and calcium overload, with both of them contributing to the mitochondria-dysfunction-associated eradication of tumor cells.