Localizing subcellular objects in 3D at high throughput is a major challenge in microscopy with broad relevance to biology and medicine. By merging two technologies, point-spread-function engineering and imaging flow cytometry, we have accelerated 3D imaging to record large populations of cells.

Nanotechnologies and microbiome are both important fields in novel cancer therapy. Linking these two fields together, we asked what opportunities may exist? Our recent review discusses key opportunities in applying nanotechnologies towards manipulating the microbiome for cancer treatment.

With a need to develop new non-opioid analgesics, pH-responsive nanoparticles may offer an alternative strategy for improving analgesic drug efficacy and duration of action.