Dynamic gene expression patterns orchestrate cellular functions. To understand the link between dynamic behaviour and cellular phenotype, and to direct cell fate in a user-defined way, tools enabling precise tuning of gene activation levels and temporal dynamics were developed.
In the eye, a tiny pit in the central retina provides us the clearest vision of all. This region contains the highest number of cone photoreceptors – responsible for our daylight, high acuity vision. Unfortunately, several diseases lead to the degeneration of these photoreceptor cells.
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