Behind the Paper
The real stories behind the latest research papers, from conception to publication, the highs and the lows
Gene expression tuning made easy
Have you ever wished to tune endogenous gene expression? Wait no longer.
In this “Behind the paper” blog post, I will present you our new toolkit, CasTuner, which is specifically designed to tune endogenous gene expression. I will summarize how CasTuner works, how to and why you should use it.
A quantitative peek into the superresolution subcellular world
Incorporating a physical model differentiating in-focus and out-of-focus emissions eliminates background fluorescence without affecting genuine signals. With this added to the sparse deconvolution pipeline, we preserve weak signals and minimize artifacts while achieving a sub-70 nm resolution.
Organoids facilitate studies on crosstalk of niches and adult stem cells
Our new paper published on npj Regenerative Medicine provides new insight to the role of macrophages on mammary stem cell fate determination and mammary homeostasis maintanence.
