How living organisms perceive and transduce signals is a fundamental question in life sciences. Particularly, the ability to sense and discriminatively respond to nutrient and toxic ions is crucial for survival of all organisms, which is especially true for non-motile plants.
How we created the biggest animal bite force database to date
Follow us on our way to the creation of the bite force database for 654 insect species!
Computational pathology identifies immune-mediated collagen disruption to predict clinical outcomes in gynecologic malignancies
A computational pathology tool to quantitatively characterize the immune-collagen relationship in gynecologic cancers. It enables prognostic stratification of patients and provides insights into the biology of the tumor microenvironment.
Safety and Feasibility of Anti-CD19 CAR T Cells Expressing Inducible IL-7 and CCL19 in Patients with Relapsed or Refractory Large B-cell Lymphoma
In this study, Lei et al. first report the preclinical and the phase 1 clinical trial results of CD19-specific CAR-T cells capable of expressing interleukin (IL)-7 and chemokine (C-C motif) ligand (CCL)-19 ( 7 × 19 CAR-T cells) in patients with R/R LBCL.