We stumble upon an iterative optimization of fluorescence images followed by the RL deconvolution using the spatiotemporal continuity and sparsity prior knowledge. This Sparse deconvolution algorithm can extend spatial resolutions of fluorescence microscopes beyond their hardware constraints.
We developed a new type of MOFs-based core-shell nanoagents that enables near infrared (NIR) light-triggered two distinct antitumor mechanisms, namely oxidative stress and calcium overload, with both of them contributing to the mitochondria-dysfunction-associated eradication of tumor cells.
Photothermal nanofibers were developed comprised of light-sensitive iron oxide nanoparticles (IONPs) embedded in electrospun nanofibers. We demonstrated that embryonic stem cells and human T cells, transfected with such nanofibers are in excellent health and retain their therapeutic functionality.
We designed nanofibers that incorporate the tetrodotoxin binding peptide sequences from the voltage-gated sodium channel. These nanofibers allowed the specific binding and release of tetrodotoxin to achieve prolonged nerve blockade.
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