Jointly acting gene variants in cardiomyopathy
Genome-edited human pluripotent stem cells and genome-edited mouse models reveal that combinatorial genetic interactions contribute to the complex genetic heritability of human cardiomyopathy.
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The cover illustrates that two genetic variants found in patients with dilated cardiomyopathy jointly contribute to the complex genetic heritability of the disease.
See Deacon et al.
Image: Chao Chen, UCSD. Cover design: Allen Beattie.