Amplification-free nucleic-acid testing

An electrical biosensor combining CRISPR/Cas9 and a graphene field-effect transistor detects target genes in purified genomic samples at high sensitivity, within 15 minutes, and without the need for amplification.

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Pep Pàmies

Chief Editor, Nature Biomedical Engineering, Nature Research

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Go to the profile of Pep Pàmies
over 2 years ago

The cover illustrates an electrical biosensor for nucleic acids that relies on the binding of target sequences to Cas9 immobilized on a graphene field-effect transistor.


See Hajian et al.

Image: Ella Maru Studio.