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Amplification-free nucleic-acid testing

An electrical biosensor combining CRISPR/Cas9 and a graphene field-effect transistor detects target genes in purified genomic samples at high sensitivity, within 15 minutes, and without the need for amplification.
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Go to the profile of Pep Pàmies
Pep Pàmies
Chief Editor, Nature Biomedical Engineering, Nature Research
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Detection of unamplified target genes via CRISPR–Cas9 immobilized on a graphene field-effect transistor - Nature Biomedical Engineering

An electrical biosensor combining CRISPR–Cas9 and a graphene field-effect transistor detects target genes in purified genomic samples at high sensitivity, within 15 minutes, and without the need for amplification.
Go to the profile of Pep Pàmies
Pep Pàmies
Chief Editor, Nature Biomedical Engineering, Nature Research

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Go to the profile of Pep Pàmies
Pep Pàmies
about 3 years ago

The cover illustrates an electrical biosensor for nucleic acids that relies on the binding of target sequences to Cas9 immobilized on a graphene field-effect transistor.

See Hajian et al.

Image: Ella Maru Studio.


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