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Accelerated discovery of antiviral antibodies

An antibody-discovery pipeline integrating single-cell mRNA-sequence analysis, bioinformatics, synthetic biology and high-throughput functional analyses enables the rapid discovery of potent human monoclonal antibodies against viral pathogens.
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Go to the profile of Pep Pàmies
Pep Pàmies
Chief Editor, Nature Biomedical Engineering, Nature Research
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Integrated pipeline for the accelerated discovery of antiviral antibody therapeutics - Nature Biomedical Engineering

An antibody-discovery pipeline integrating single-cell mRNA-sequence analysis, bioinformatics, synthetic biology and high-throughput functional analyses enables the rapid discovery of potent human monoclonal antibodies against viral pathogens.
Go to the profile of Pep Pàmies
Pep Pàmies
Chief Editor, Nature Biomedical Engineering, Nature Research

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Go to the profile of Pep Pàmies
Pep Pàmies
about 2 years ago

The cover illustrates antiviral human monoclonal antibodies, in this case against the Zika virus, discovered via a pipeline integrating single-cell mRNA-sequence analysis, bioinformatics, synthetic biology and high-throughput functional analyses.

See Gilchuk et al.

Image: Molecular structures from David S. Goodsell and the RCSB PDB. Cover design: Alex Wing.

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