Accelerated discovery of antiviral antibodies

An antibody-discovery pipeline integrating single-cell mRNA-sequence analysis, bioinformatics, synthetic biology and high-throughput functional analyses enables the rapid discovery of potent human monoclonal antibodies against viral pathogens.

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Pep Pàmies

Chief Editor, Nature Biomedical Engineering, Nature Research

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Pep Pàmies 29 days ago

The cover illustrates antiviral human monoclonal antibodies, in this case against the Zika virus, discovered via a pipeline integrating single-cell mRNA-sequence analysis, bioinformatics, synthetic biology and high-throughput functional analyses.

See Gilchuk et al.

Image: Molecular structures from David S. Goodsell and the RCSB PDB. Cover design: Alex Wing.