The cover illustrates that the tagging of tumour cells with an amphiphilic ligand for a chimaeric antigen receptor on T cells allows for the universal redirection of the cells against solid tumours.
Antigen-agnostic tumour tagging for CAR T cell therapy
T cells with a chimaeric antigen receptor specific for fluorescein isothiocyanate can be directed against solid tumours via the intratumoural administration of a fluorescein-isothiocyanate-conjugated amphiphile that inserts itself in cell membranes.
Published
Chief Editor, Nature Biomedical Engineering, Nature Research
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Nature Biomedical Engineering
This journal aspires to become the most prominent publishing venue in biomedical engineering by bringing together the most important advances in the discipline, enhancing their visibility, and providing overviews of the state of the art in each field.
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