The cover illustrates a microfluidic cartridge for the automated amplification and detection of SARS-CoV-2 RNA in saliva via the Cas13-mediated cleavage of a quenched fluorophore.
Automated Cas13-based detection of SARS-CoV-2 in saliva
A COVID-19 test implemented in an automated microfluidic device and leveraging isothermal RNA amplification followed by T7 transcription and Cas13-mediated cleavage of a quenched fluorophore rapidly detects SARS-CoV-2 RNA in saliva samples.
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