The cover illustrates that, in cardiomyocytes under contraction, epigenetically marked chromatin preferentially accumulates in the periphery of the cell’s nucleus.
Nuclear mechanosensing and chromatin reorganization in cardiac cells
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Nuclear deformation guides chromatin reorganization in cardiac development and disease - Nature Biomedical Engineering
Strain maps of cardiomyocyte nuclei during contraction indicate that, by integrating environmental mechanical cues, the nuclei of cardiomyocytes stabilize the fate of cells through the reorganization of epigenetically marked chromatin.
Nature Biomedical Engineering
This journal aspires to become the most prominent publishing venue in biomedical engineering by bringing together the most important advances in the discipline, enhancing their visibility, and providing overviews of the state of the art in each field.