The cover illustrates that a scaffold releasing specific small molecules and antibodies can suppress regulatory T cells and attract and stimulate effector T cells when implanted peritumourally in mice.
Peritumoural immunomodulatory scaffolds
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Systemic enhancement of antitumour immunity by peritumourally implanted immunomodulatory macroporous scaffolds - Nature Biomedical Engineering
A peritumourally implanted macroporous scaffold releasing small molecules and antibodies to suppress regulatory T cells and to attract and stimulate effector T cells enhanced endogenous antitumoural responses in mice bearing aggressive tumours.