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Prime editing of pathogenic mutations in mouse eyes and livers

In mouse models of hereditary tyrosinaemia and of Leber congenital amaurosis, prime editing can precisely correct the disease-causing mutations, ameliorating the disease phenotypes.
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Pep Pàmies
Chief Editor, Nature Biomedical Engineering, Nature Research
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Application of prime editing to the correction of mutations and phenotypes in adult mice with liver and eye diseases - Nature Biomedical Engineering

In mouse models of hereditary tyrosinaemia and of Leber congenital amaurosis, prime editing can precisely correct the disease-causing mutations, ameliorating the disease phenotypes.

See Jang et al.

Image: Heather B. McDonald. Cover design: Alex Wing.
Go to the profile of Pep Pàmies
Pep Pàmies
Chief Editor, Nature Biomedical Engineering, Nature Research

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