Prolonged immune activation via polymer–STING condensates

A polyvalent STING agonist prolongs the activation of innate-immunity pathways through the formation of STING condensates, and leads to synergistic therapeutic outcomes in vivo when combined with the STING ligand cGAMP.

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Image: Xianzhi Chen, Shenyang Zhiyan Science and Technology Co. Ltd. Cover design: Allen Beattie.

Pep Pàmies

Chief Editor, Nature Biomedical Engineering, Nature Research