Contributor Nature Biotech

Harnessing the intracellular triacylglycerols for titer improvement of polyketides in Streptomyces

Pharmaceutically important polyketides are produced during the stationary phase of growth of Streptomyces species in fermenters. The source of intracellular metabolites that are funneled into polyketide biosynthesis has proven elusive. We uncover the mystery and devised a titer improvement strategy.
Go to the profile of Shanshan Li
Dec 12, 2019