A community from Nature Biomedical Engineering

Mark A. Kay

Professor of Pediatrics and Genetics , Stanford University

Stanford University
United States of America

Subject

Delivery of drugs, molecules or cells Drug and cell delivery Epigenetics Genetic engineering Genomic engineering Genomics Molecular and cell engineering Nucleic acid therapies Protein engineering Tissue engineering Translational medicine

AAV- homologous recombination based therapeutics

Recombinant AAV vectors are becoming more popular for therapeutic genome editing. We describe a clinically relevant approach to enhance insertion a therapeutic sequence into almost any site in the host genome.